Coumarins and alkaloids in shoot culture of Ruta graveolens L.

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[Acridine-alkaloids from callus cultures of Ruta graveolens L].

Rutacridone, 1-hydroxy-A-methylacridone, and l-hydroxy-3-methoxy-A-methylacridone have been isolated for the first time from callus cultures, which had been obtained from meristematic stem cells of Ruta graveolens L. The alkaloids were identified by co-chromatography with authentic compounds, by IR spectra, and by electronic spectra before and after addition of A1C13 . The use of the bathochrom...

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Volatile Composition of Ruta graveolens L. of North of Iran

The chemical constituents of the essential oil of Ruta graveolens L. from aerial parts collected from Iran were analyzed by GC and GC/MS. The oil yield of the dried plant obtained by hydrodistillation was 0.4% (v/w). Nineteen compounds, representing for 95.2% of the oil, were identified. The main classes of compounds were found to be ketons(46.6%) and sesquiterpenoids (13.3%) and monoterpenoids...

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Biosynthesis of Acridone Alkaloids. A Cell-Free System from Ruta graveolens Cell Suspension Cultures

Ruta graveolens, Suspension Cultures, Cell-Free System, Acridone Biosynthesis, 1,3-DihydroxyN-methylacridone A cell-free extract of Ruta graveolens cell suspension cultures, strain R-20, was prepared which synthesizes 1,3-dihydroxy-N-methylacridone from N-methylanthranilic acid and malonylcoenzyme A. The reaction is strongly dependent on the presence of ATP. After adding of coenzyme A to the as...

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Anti-tumour activity of Ruta graveolens extract.

An extract of Ruta graveolens was found to be cytotoxic to Dalton's lymphoma ascites (DLA), Ehrlich ascites carcinoma (EAC) and L929 cells in culture (IC100=16 mg/ml) and also to increase the lifespan of tumour bearing animals. The extract further decreased solid tumours developing from DLA and EAC cells when given simultaneously with elongation of the lifespan of tumour-bearing animals. A home...

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Acute Effects of Ruta graveolens L. on Sperm Parameters and DNA Integrity in Rats

BACKGROUND Increase in world population is one of the serious and threatening issues in this century. Therefore, it is vitally important to find safe and effective contraceptive methods, especially for men which already have few choices in this regard. Medicinal plants that were used for contraception in ancient times could be good sources of investigation in this filed. Ruta graveolens L. is o...

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ژورنال

عنوان ژورنال: Acta Societatis Botanicorum Poloniae

سال: 2014

ISSN: 2083-9480

DOI: 10.5586/asbp.1997.039